Clinical research

PICOT is an acronym used to help develop clinical research questions and guide you in your search for evidence:

P = Patient population

I = Intervention or issue of interest

C = Comparison of interventions or comparison of interests

O = Outcome

T = Time frame

For example, you may wish to research if the timing of IV tubing  changes affects the development of CLABSI, using this PICOT model:

In _____(P), what is the effect of _____(I) on ____(O) compared with _____(C) within ______ (T)?

In patients on the acute care medical surgical floor (P), what is the  effect of changing continuous IV tubings every 96 hours (I) on the  incidence of CLABSI (O) versus every changing continuous IV tubings  every 48 hours (C) during a 6-month tracking period (T)?

Assignment Directions

Begin by selecting a topic in nursing or medicine that is of interest  to you. Next, use PICOT to format possible research questions about  that topic. Provide three possible PICOT research questions related to  the chosen topic (each question will have a different direction on the  same topic).

Include the following: 

  • Provide a brief description of the topic and background information.
  • Explain the significance of the topic to nursing practice.
  • Provide three clearly stated PICOT questions.

Your paper should: 

  • 3 pages
  • Use current APA Style to format your paper and to cite your sources.